Genetic Testing Newcastle
Genetic testing looks at your DNA for inherited gene changes that can raise the risk of prostate cancer, particularly aggressive or early-onset disease. Delivered in partnership with Informed Genomics, it is a simple saliva test that can guide your screening, your treatment and your family’s awareness.
What is genetic testing for prostate cancer?
Genetic testing for prostate cancer examines your DNA for specific inherited mutations. These are changes in certain genes such as BRCA1, BRCA2, HOXB13 and genes linked to Lynch syndrome that are associated with a higher risk of prostate cancer.
Some inherited gene changes are linked not only with a higher lifetime risk but also with earlier onset or more aggressive disease.
Knowing whether you carry one of these gene changes can help in several ways:
- It can guide when to begin prostate cancer screening and how closely to monitor you
- It can influence treatment decisions if prostate cancer is diagnosed, including eligibility for certain targeted therapies
- It can provide important information for close relatives, as inherited gene changes can be passed down through families
Testing is provided in partnership with Informed Genomics. It is designed to be clear, convenient and discreet, with proper specialist interpretation and counselling support.
How it works
Genetic testing identifies inherited gene changes that may increase prostate cancer risk.
Saliva sample collection
A simple saliva kit is sent to your home or provided in clinic. No blood test is required.
Laboratory analysis
Your DNA is analysed for specific inherited gene mutations known to be linked with prostate cancer risk.
Results with counselling
Results are usually available within four to six weeks. If a significant finding is identified, a specialist genetic counsellor explains what it means and discusses next steps
How genetic testing differs from prostate cancer risk screening
Genetic testing and prostate cancer risk screening answer different questions and may complement each other.
Genetic inherited testing
Looks for specific high-risk gene mutations that run in families and increase the likelihood of aggressive prostate cancer. It is particularly relevant where there is a strong personal or family history.
Polygenic risk screening
Our polygenic risk score assesses many common gene variants to estimate overall inherited risk and personalise your screening schedule. Both approaches can help refine how and when you are monitored.
Who genetic testing may suit
Genetic testing may be especially worth considering if you have:
- A personal history of prostate cancer, particularly diagnosed before the age of 55 or with aggressive features
- A father, brother or son diagnosed with prostate cancer
- A family history of breast, ovarian or pancreatic cancer
- A known BRCA, HOXB13 or Lynch syndrome gene change in your family
- Ashkenazi Jewish ancestry, where certain inherited gene changes are more common
A consultation will clarify whether testing is appropriate in your circumstances.
What to expect
- Arrange your test
Following discussion with your consultant, a saliva collection kit is sent to your home or you can provide a sample in clinic. - Laboratory analysis
Informed Genomics analyses your sample for inherited gene changes associated with prostate cancer risk. - Results and counselling
Results are typically available within four to six weeks. If a clinically significant mutation is identified, a specialist genetic counsellor explains the implications for you and potentially for your family.
Why choose The Forbury Clinic for genetic testing in Newcastle?
Insight you can act on
Results can help tailor screening schedules and inform future treatment decisions if required.
Valuable information for your family
Inherited gene changes can be shared by close relatives. Identifying them can support awareness and early monitoring.
Simple and discreet
A straightforward saliva test carried out at home or in clinic without a blood draw.
Properly supported interpretation
Significant results are explained with specialist genetic counselling rather than left for you to interpret alone.
Frequently asked questions
Is this the same as prostate cancer screening?
No. Genetic testing looks for specific inherited gene mutations that run in families. Polygenic risk screening estimates overall inherited risk from many smaller gene variations. They address different aspects of risk and may both be useful.
Does a positive result mean I will develop prostate cancer?
No. A positive result means your inherited risk is higher than average. It does not mean you will definitely develop prostate cancer. It helps guide closer monitoring and informed decisions.
Will my results affect my family?
They may. If an inherited gene change is identified, close relatives could also carry it. A genetic counsellor will explain how and whether family members might consider testing.
How is the test performed?
It involves a simple saliva sample collected at home or in clinic. Results usually take around four to six weeks.
Book your urology consultation today
Consultations are available to book online for patients with or without a GP referral. Our private specialists provide world-class care in a discrete environment.
- AppointmentBook a consultation
- Reception01189207055
- Location
The Beverley Hospital, The Edge, Fifth Ave, Team Valley, Gateshead NE11 0XA
