Perovial for Peyronie’s Disease Newcastle
A minimally invasive injectable treatment that uses high‑purity hyaluronic acid to soften plaque, reduce penile curvature and ease the pain of Peyronie’s disease. Particularly suited to the active phase, it offers a non‑surgical option for selected men.
What is Perovial?
Perovial is an injectable treatment for Peyronie’s disease based on high‑purity hyaluronic acid. It is an EMA‑approved injectable device indicated for use in the acute or active phase of the condition.
In Peyronie’s disease, fibrous scar tissue known as plaque forms within the penis. This can cause curvature, pain and difficulty with erections. During the active phase, curvature may worsen and discomfort is often more noticeable.
Perovial is injected directly into the plaque. The aim is to soften the scar tissue and support repair of the surrounding tissue, helping to reduce curvature and relieve pain.
Hyaluronic acid is a substance naturally present in the body. It retains water and supports tissue elasticity, which is why it is used to improve flexibility within affected areas.
Perovial is offered as part of a broader Peyronie’s disease pathway. Your consultant will confirm whether you are in the active phase and whether this treatment is appropriate for you.
Three ways hyaluronic acid helps
Perovial works through the properties of hyaluronic acid delivered directly into the plaque.
Anti‑inflammatory support
Helps reduce inflammation and oxidative stress that contribute to disease progression.
Anti‑fibrotic effect
Aims to limit excess collagen build‑up associated with plaque formation and rigidity.
Tissue hydration
Draws and retains water within the tissue, helping to improve elasticity and soften plaque. Treatment is delivered as a structured course, allowing gradual improvement over time.
Who Perovial may suit
Perovial is intended for men with Peyronie’s disease in the acute or active phase, particularly those experiencing:
- Worsening or unstable penile curvature
- Pain during erections
- Early impact on sexual function
- A preference to avoid surgery
- A desire to act early in the disease course
Assessment confirms suitability and stage of disease before treatment begins.
What to expect
- Initial consultation
A specialist assessment confirms that you are in the active phase and that Perovial is suitable for you. - Weekly injections
A course of 10 injections is given at weekly intervals directly into the plaque in clinic. - Review and monitoring
Curvature, pain and response are monitored throughout the course to assess improvement.
Why choose The Forbury Clinic for Perovial in Newcastle?
Less invasive than surgery
A non‑surgical option that may reduce curvature and pain without operative correction.
Targeted plaque treatment
Delivered directly into the scar tissue rather than relying on systemic medication.
Structured and monitored course
Treatment is delivered as a defined programme with regular review.
Consultant‑led care
Assessment and injections are performed by a specialist experienced in managing Peyronie’s disease.
From assessment to improvement
Perovial is most effective when used during the active phase of Peyronie’s disease.
Not every man with Peyronie’s disease is a candidate for injectable treatment. In stable or long‑standing curvature, surgical options may be more appropriate.
Treatment decisions are based on disease stage, severity and personal goals.
Frequently asked questions
What is Peyronie’s disease?
A condition in which fibrous plaque forms inside the penis causing curvature and sometimes pain or erectile difficulty.
How many injections will I need?
The usual course consists of 10 injections given one week apart.
Is the treatment painful?
The injection is placed directly into the plaque. Any discomfort is typically brief and explained clearly beforehand.
Is Perovial right for me?
It is designed for men in the acute phase. A consultation confirms suitability.
Is it an alternative to surgery?
Yes. In the active phase, Perovial may help reduce curvature and pain and may delay or avoid the need for surgery in selected cases.
Book your urology consultation today
Consultations are available to book online for patients with or without a GP referral. Our private specialists provide world-class care in a discrete environment.
- AppointmentBook a consultation
- Reception01189207055
- Location
The Beverley Hospital, The Edge, Fifth Ave, Team Valley, Gateshead NE11 0XA
