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The Forbury Clinic

Prostate Cancer Screening in Newcastle

Personalised and consultant-led prostate cancer screening that combines PSA testing and MRI with advanced genetic risk assessment in partnership with Antegenes. The result is a clearer understanding of your prostate health and a screening plan built around your individual risk before symptoms appear.

  • From age 40

    Personalised to your risk
    PSA, MRI and genetic risk
    Simple at-home saliva test
    In partnership with Antegenes

A smarter way to screen for prostate cancer

Prostate cancer is the most common cancer in men in the UK, with more than 55,000 new cases diagnosed each year. It often develops slowly and may cause no symptoms in its early stages. The purpose of screening is to detect cancers that need attention early while avoiding unnecessary investigation where risk is low.

The PSA blood test remains an important screening tool. However, PSA has limitations. Levels can be raised for benign reasons such as enlargement or infection, and occasionally remain within the normal range even when cancer is present. Relying on PSA alone can therefore either cause unnecessary worry or provide false reassurance.

Our screening approach adds a genetic dimension. Research suggests that around half of prostate cancer risk is inherited, even when there is no known family history. We offer a polygenic risk score in partnership with Antegenes. This complements PSA and MRI rather than replacing them.

Your consultant brings together PSA, imaging and genetic insight into one clear recommendation about when screening should begin, how often it should be repeated and which investigations are appropriate for you.

Three strands, one clear picture

What the assessment looks at

Screening is matched to you rather than to population averages.

PSA blood test

A well-established blood test that can flag changes in the prostate. It is interpreted in context rather than in isolation.

MRI where appropriate

Multiparametric MRI provides detailed imaging of the prostate and can identify areas that warrant closer assessment.

Genetic risk score

An Antegenes polygenic risk score estimates your inherited risk. This information cannot be obtained from PSA or MRI alone.

What is a polygenic risk score?
A polygenic risk score assesses the combined effect of many common genetic variants linked to prostate cancer. Each individual variant has a small influence, but together they provide a meaningful estimate of lifetime inherited risk. The test uses a simple saliva sample.

It is non-invasive and only needs to be performed once in a lifetime because your genetic makeup does not change. The result is not diagnostic. It does not detect cancer. Instead, it helps determine whether you may benefit from earlier or more frequent screening. Your consultant interprets the score alongside age, ethnicity and family history to build a personalised plan.

Who prostate cancer screening may suit

Personalised prostate cancer screening in Newcastle may be particularly worth considering if you:

  • Are aged 40 or over
  • Have a father or brother with prostate cancer
  • Are of Black or Afro-Caribbean heritage
  • Want greater clarity than PSA testing alone can provide

Men without symptoms may still benefit from proactive assessment, especially where risk factors are present.

What to expect

  1. Arrange your test and provide a sample
    After enquiry, a saliva kit is sent to your home or provided in clinic. You return the sample securely.
  2. Laboratory analysis
    The sample is processed in an accredited laboratory analysing more than 100 genetic markers associated with prostate cancer risk.
  3. Results and consultant plan
    Results are typically available within six to eight weeks. Your consultant reviews them with you and recommends a personalised screening schedule.

Why choose The Forbury Clinic for the Optilume procedure in Newcastle?

Why The Forbury Clinic
1

Accurate stricture assessment

Treatment is guided by precise definition of length, position and cause.

2

Minimally invasive option

A day-case procedure with faster recovery than reconstructive surgery.

3

Honest discussion of durability

Clear explanation of recurrence rates and when urethroplasty may still be preferable.

4

Consultant-led throughout

Assessment, procedure and follow-up are delivered by an experienced urologist.

From assessment to plan

Screening usually begins with discussion of risk factors and PSA testing. Genetic risk assessment adds further clarity about your inherited susceptibility.

MRI is used where appropriate to refine risk or investigate PSA changes.

Not every man needs every test. Screening is tailored rather than routine.

The outcome is a clear plan. Some men require closer monitoring with more frequent PSA or imaging. Others can space checks confidently at longer intervals.

How your results guide your care

If your inherited risk is higher

More frequent PSA testing or earlier MRI may be recommended along with proactive monitoring.

If your inherited risk is lower

Screening intervals can be extended with confidence, reducing unnecessary tests and anxiety.

Either way, you leave with clarity and a structured approach to long-term prostate health.

Frequently asked questions

Do I need to visit the clinic for the genetic test?

Not necessarily. Most men complete the saliva test at home. A clinic appointment is arranged if discussion is needed or preferred.

Is this the same as BRCA testing?

No. A polygenic risk score assesses common genetic variants. Testing for rare mutations such as BRCA1 or BRCA2 is separate and may be advised where there is a strong family history.

Is the genetic test diagnostic?

No. It measures inherited risk and does not detect cancer. It guides screening rather than replacing PSA or MRI.

Can I have this if my PSA is normal?

Yes. The genetic assessment may highlight increased inherited risk even when PSA is within the normal range.

At what age should I start?

Screening is often considered from around age 40, or earlier where there are higher-risk factors such as family history or ethnicity.

Do I need a GP referral?

No. Self-referral is welcome and appointments can be arranged directly.

Reviewed by Mr Matthew B.K. Shaw
Mr Shaw qualified from Oriel College, University of Oxford in 1997 before developing an internationally recognised Urology practice in the North East of England.
Last reviewed: 21 Jul 2026.

Book your urology consultation today

Book an Appointment

Consultations are available to book online for patients with or without a GP referral. Our private specialists provide world-class care in a discrete environment.

  • Appointment
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  • Reception
    01189207055
  • Location

    The Beverley Hospital, The Edge, Fifth Ave, Team Valley, Gateshead NE11 0XA

Treatment suitability is determined following consultation with a specialist. Individual results and recommendations vary.
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