UTI Vaccine (Uromune) in Newcastle
Uromune is a UTI vaccine. It is a sublingual treatment designed to help your immune system prevent recurrent urinary tract infections, offering an alternative to repeated courses of antibiotics. It is prescribed after specialist assessment.

What is the Uromune UTI vaccine?
Uromune is a vaccine designed to help prevent recurrent urinary tract infections by supporting the body’s own immune response.
Unlike antibiotics, which treat an infection once it has developed, Uromune aims to reduce the likelihood of infections returning.
It is taken as a daily spray under the tongue, usually for around three months. The vaccine contains inactivated forms of bacteria most commonly responsible for UTIs. These stimulate the immune system, particularly at the lining of the urinary tract, to recognise and clear bacteria more effectively.
Recurrent UTIs are increasingly understood to involve changes in the local immune response within the bladder. A vaccine approach is designed to strengthen this response.
Uromune can be considered for women, men and in selected cases children, including people with more complex urinary problems.
In the UK, Uromune is an unlicensed medicine. This means it is prescribed on a named-patient basis by a specialist consultant following full assessment. Your consultant will explain what this means and whether it is appropriate in your case.

How it works
Uromune is designed to work with your immune system.
Targets common bacteria
The vaccine contains inactivated forms of the bacteria most often responsible for UTIs, focusing the immune response where it matters.
Stimulates immune recognition
Taken under the tongue, it encourages the body to recognise and respond more effectively to these bacteria at the lining of the urinary tract.
Aims to reduce recurrence
The goal is fewer infections over time and reduced reliance on repeated antibiotic courses.
Who the UTI vaccine may suit
Uromune may be considered for people who:
- Experience recurrent urinary tract infections
- Prefer an alternative to repeated or long-term antibiotics
- Have complex UTIs including catheter use or neurogenic bladder
- Have been assessed as suitable by a specialist consultant
A detailed review of your infection history and previous treatments is essential before prescribing.
What to expect
- Specialist assessment
Your consultant will review your infection pattern and previous investigations. The named-patient basis and unlicensed status are discussed clearly. - Three-month course
If appropriate, you take the vaccine as a daily sublingual spray for around three months at home. - Review and follow-up
Your consultant will monitor your response. Some people consider a repeat course after one to two years if infections begin to recur.
Uromune has been evaluated in clinical studies and long-term follow-up data.
Published research reports that:
Long-term UK follow-up has shown that some patients remain infection-free for several years, while others experience fewer and less severe episodes.
Individual outcomes vary. Your consultant will explain what is realistic for your situation.
Why choose The Forbury Clinic for a UTI vaccine consultation in Newcastle?
Alternative to repeated antibiotics
Supports immune defence rather than relying solely on antibiotics.
Addresses recurrence
Targets the immune response within the urinary tract, which is thought to contribute to recurrent infections.
Consultant-led prescribing
Provided only after careful specialist assessment and review of your infection history.
Part of a wider prevention plan
Used alongside other measures such as lifestyle advice and, where appropriate, further investigation.
Frequently asked questions
Is Uromune really a vaccine?
Yes. It stimulates your immune system to recognise bacteria that commonly cause UTIs. It is taken under the tongue rather than given as an injection.
Is it available in the UK?
Yes, but it is unlicensed. It is prescribed on a named-patient basis by a specialist consultant following assessment.
How effective is it?
Clinical studies have shown a higher proportion of patients remaining infection-free compared with placebo and sustained reductions in recurrence in follow-up data. Individual results vary.
How is it different from antibiotics?
Antibiotics treat active infection. Uromune aims to prevent infections from recurring by strengthening immune response.
Can I have it without seeing a specialist?
No. Because it is supplied on a named-patient basis, prescription follows specialist consultation and assessment.

Book your urology consultation today
Consultations are available to book online for patients with or without a GP referral. Our private specialists provide world-class care in a discrete environment.
- AppointmentBook a consultation
- Reception01189207055
- Location
The Beverley Hospital, The Edge, Fifth Ave, Team Valley, Gateshead NE11 0XA
