Get in Touch - We're here to help
The Forbury Clinic

UTI Vaccine (Uromune) in Newcastle

Uromune is a UTI vaccine. It is a sublingual treatment designed to help your immune system prevent recurrent urinary tract infections, offering an alternative to repeated courses of antibiotics. It is prescribed after specialist assessment.

  • A vaccine, not an antibiotic
  • Pioneered in the UK
    A sublingual UTI vaccine
    Aims to reduce recurrence
    Prescribed after specialist assessment
    Part of a consultant-led plan

What is the Uromune UTI vaccine?

Uromune is a vaccine designed to help prevent recurrent urinary tract infections by supporting the body’s own immune response.

Unlike antibiotics, which treat an infection once it has developed, Uromune aims to reduce the likelihood of infections returning.

It is taken as a daily spray under the tongue, usually for around three months. The vaccine contains inactivated forms of bacteria most commonly responsible for UTIs. These stimulate the immune system, particularly at the lining of the urinary tract, to recognise and clear bacteria more effectively.

Recurrent UTIs are increasingly understood to involve changes in the local immune response within the bladder. A vaccine approach is designed to strengthen this response.

Uromune can be considered for women, men and in selected cases children, including people with more complex urinary problems.

In the UK, Uromune is an unlicensed medicine. This means it is prescribed on a named-patient basis by a specialist consultant following full assessment. Your consultant will explain what this means and whether it is appropriate in your case.

How it works

What it involves

Uromune is designed to work with your immune system.

Targets common bacteria

The vaccine contains inactivated forms of the bacteria most often responsible for UTIs, focusing the immune response where it matters.

Stimulates immune recognition

Taken under the tongue, it encourages the body to recognise and respond more effectively to these bacteria at the lining of the urinary tract.

Aims to reduce recurrence

The goal is fewer infections over time and reduced reliance on repeated antibiotic courses.

Who the UTI vaccine may suit

Uromune may be considered for people who:

  • Experience recurrent urinary tract infections
  • Prefer an alternative to repeated or long-term antibiotics
  • Have complex UTIs including catheter use or neurogenic bladder
  • Have been assessed as suitable by a specialist consultant

A detailed review of your infection history and previous treatments is essential before prescribing.

What to expect

  1. Specialist assessment
    Your consultant will review your infection pattern and previous investigations. The named-patient basis and unlicensed status are discussed clearly.
  2. Three-month course
    If appropriate, you take the vaccine as a daily sublingual spray for around three months at home.
  3. Review and follow-up
    Your consultant will monitor your response. Some people consider a repeat course after one to two years if infections begin to recur.

Uromune has been evaluated in clinical studies and long-term follow-up data.

The evidence

Published research reports that:

56%
Around 56 to 58 percent of patients remaining free of UTIs during a study period compared with approximately 25 percent on placebo
UTI Episodes
A reduction in median UTI episodes from three to none during the study period
Infections
Sustained reductions in infections over several years of follow-up in real-world settings
Safety
A strong safety and tolerability profile in published data

Long-term UK follow-up has shown that some patients remain infection-free for several years, while others experience fewer and less severe episodes.

Individual outcomes vary. Your consultant will explain what is realistic for your situation.

Why choose The Forbury Clinic for a UTI vaccine consultation in Newcastle?

Why The Forbury Clinic
1

Alternative to repeated antibiotics

Supports immune defence rather than relying solely on antibiotics.

2

Addresses recurrence

Targets the immune response within the urinary tract, which is thought to contribute to recurrent infections.

3

Consultant-led prescribing

Provided only after careful specialist assessment and review of your infection history.

4

Part of a wider prevention plan

Used alongside other measures such as lifestyle advice and, where appropriate, further investigation.

Frequently asked questions

Is Uromune really a vaccine?

Yes. It stimulates your immune system to recognise bacteria that commonly cause UTIs. It is taken under the tongue rather than given as an injection.

Is it available in the UK?

Yes, but it is unlicensed. It is prescribed on a named-patient basis by a specialist consultant following assessment.

How effective is it?

Clinical studies have shown a higher proportion of patients remaining infection-free compared with placebo and sustained reductions in recurrence in follow-up data. Individual results vary.

How is it different from antibiotics?

Antibiotics treat active infection. Uromune aims to prevent infections from recurring by strengthening immune response.

Can I have it without seeing a specialist?

No. Because it is supplied on a named-patient basis, prescription follows specialist consultation and assessment.

Reviewed by Mr Matthew B.K. Shaw
Mr Shaw qualified from Oriel College, University of Oxford in 1997 before developing an internationally recognised Urology practice in the North East of England.
Last reviewed: 21 Jul 2026.

Book your urology consultation today

Book an Appointment

Consultations are available to book online for patients with or without a GP referral. Our private specialists provide world-class care in a discrete environment.

  • Appointment
    Book a consultation
  • Reception
    01189207055
  • Location

    The Beverley Hospital, The Edge, Fifth Ave, Team Valley, Gateshead NE11 0XA

Treatment suitability is determined following consultation with a specialist. Individual results and recommendations vary.
Contact Form